The UILO is actively engaged in the creation and development of UBC spin-off companies, based on UBC research discoveries. As at March 31, 2012, UBC research has been instrumental in creating 153 spin-off companies.
Below is a list of those companies understood to be currently active, or to have merged or been acquired.
See also the full criteria for spin-off companies.
| FY | Company | Location | Status | Sector |
| 2012 | Therabiologics | CA | Early Stage | Life Sciences |
| 2012 | Traumis | BC | Early Stage | Life Sciences |
| 2012 | LionsGate Technologies | BC | Early Stage | Life Sciences |
| 2012 | Mirametrix | QC | Early Stage | Info Tech |
| 2011 | Sun Central | BC | Early Stage | Physical Science |
| 2011 | Veridae Systems acquired by Tektronix | BC | Acquired | Info Tech |
| 2011 | ARC Medical Devices | BC | Active | Life Sciences |
| 2011 | Computational Geoscience | BC | Active | Info Tech |
| 2011 | Precision Nanosystems | BC | Early Stage | Life Sciences |
| 2011 | ESSA Pharma Inc. | BC | Early Stage | Life Sciences |
| 2011 | Valacor Therapeutics acquired by Dermira Inc. | BC | Acquired | Life Sciences |
| 2011 | Innovative Food Systems | BC | Active | Physical Science |
| 2010 | Cloudburst Research Inc. | BC | Active | Info Tech |
| 2010 | Paragon Testing Enterprises Inc. | BC | Active | Education |
| 2010 | AlCana Technologies Inc. | BC | Active | Life Sciences |
| 2009 | Boreal Genomics Inc. | BC | Active | Life Sciences |
| 2009 | viDA Therapeutics Inc. | BC | Early Stage | Life Sciences |
| 2009 | Indel Therapeutics Inc. | BC | Early Stage | Life Sciences |
| 2009 | BioAMPS International LLC | Colorado | Early Stage | Life Sciences |
| 2009 | Dike Beheer B.V. | Netherlands | Early Stage | Life Sciences |
| 2008 | Scalable Analytics Inc. | BC | Active | Info Tech |
| 2008 | Kardium Inc. | BC | Active | Life Sciences |
| 2008 | Augurex Life Sciences Corp. | BC | Active | Life Sciences |
| 2008 | Flintbox Innovation Network Inc. Acquired by Wellspring Worldwide | BC | Acquired | Info Tech |
| 2007 | Tasktop Technologies Inc. | BC | Active | Info Tech |
| 2007 | Pacific Therapeutics Ltd. | BC | Early Stage | Life Sciences |
| 2006 | Aquinox Pharmaceuticals Inc. | BC | Early Stage | Life Sciences |
| 2006 | Ostara Nutrient Recovery Technologies Inc. | BC | Active | Physical Science |
| 2006 | Network Immunology Inc. (formerly Hoffman Technologies Inc.) | BC | Early Stage | Life Sciences |
| 2004 | Functional Technologies Corporation (formerly First Venture Technologies Corp.) | BC | Active | Life Science |
| 2003 | BrightSide (acquired by Dolby) | BC | Acquired | Physical Science |
| 2001 | VersaWave Technologies Inc. (formerlyJGKB Photonics Inc.) Acquired by Optelian | BC | Acquired | Physical Science |
| 2001 | Convergent Manufacturing Technologies Inc. | BC | Active | Physical Science |
| 2001 | OncoGenex Technologies Inc. | BC | Active | Life Science |
| 2001 | Webnames.ca, Inc. | BC | Active | Info Tech |
| 2000 | Tapimmune (formerly GeneMax Pharmaceuticals Inc.) | BC | Early Stage | Life Science |
| 2000 | D-Wave Systems Inc. | BC | Active | Info Tech |
| 2000 | Kinexus Bioinformatics Corporation | BC | Active | Life Science |
| 2000 | Xenon Pharmaceuticals (formerly Xenon Genetics Inc.) | BC | Active | Life Science |
| 1999 | Envision Sustainability Tools Inc. | BC | Active | Info Tech |
| 1999 | Membrane Reactor Technologies Ltd. Acquired by Noram | BC | Acquired | Physical Science |
| 1999 | WaveMakers Research Inc. (acquired by Harman International - 2003) | BC | Acquired | Info Tech |
| 1998 | Point Grey Research Inc. | BC | Active | Physical Science |
| 1998 | NxtPhase Corporation (formerly Carmanah Engineering) (acquired by Beacon Power Corp - April 2005) | BC | Acquired | Physical Science |
| 1998 | Raven Biotech Inc. | BC | Active | Life Science |
| 1997 | WebCT Educational Technologies Corporation (acquired by WebCT in 1999 and then Blackboard in 2006) | BC | Acquired | Info Tech |
| 1996 | MAL Manufacturing Automation Laboratories Inc. | BC | Active | Physical Science |
| 1996 | TerraGen Discovery Inc. (acquired by Cubist Pharmaceuticals - 2000) | BC | Acquired | Life Science |
| 1996 | XCERT Software Inc. (acquired by RSA Security in 2001) | BC | Acquired | Info Tech |
| 1995 | Neuromed Pharmaceuticals Inc. (formerly NeuroMed Technologies Inc.) acquired by Zalicus 2009 | BC | Acquired | Life Science |
| 1995 | NeuroVir Therapeutics Inc. (acquired by MediGene - 2000) | California | Acquired | Life Science |
| 1994 | EnWave Corporation | BC | Active | Physical Science |
| 1994 | Westport Innovations Inc. (formerly Westport Research Inc.) | BC | Active | Physical Science |
| 1993 | Forbes Medi-Tech Inc. Acquired by Pharmachem Laboratories | BC | Acquired | Life Science |
| 1993 | ImmGenics Pharmaceuticals Inc. (acquired by Abgenix - 2000) | BC | Acquired | Life Science |
| 1993 | Migenix Inc. (formerly Micrologix Biotech Inc.- 2004) Acquired by Biowest Therapeutics Inc. | BC | Acquired | Life Science |
| 1993 | Precision Biochemicals Inc. Acquired by American Radiolabeled Chemicals, Inc. in 2003 | BC | Acquired | Life Science |
| 1992 | Synapse Technologies Acquired by Biomarin Pharmaceuticals in 2002 | BC | Acquired | Life Science |
| 1992 | Cardiome Pharma Corp. (formerly Nortran Pharmaceuticals) | BC | Active | Life Science |
| 1992 | Kinetek Pharmaceuticals Inc. (acquired by QLT Inc. 2004) | BC | Acquired | Life Science |
| 1991 | ALDS Inc. | BC | Active | Physical Science |
| 1991 | Icefield Instruments Inc. | YK | Active | Physical Science |
| 1991 | ID Biomedical Corporation (acquired by GlaxoSmithKline in December 2005) | BC | Acquired | Life Science |
| 1991 | Northern Lipids Inc. | BC | Active | Life Science |
| 1990 | Aurora Instruments Ltd. | BC | Active | Physical Science |
| 1990 | Northwest Mettech Corp. | BC | Active | Physical Science |
| 1989 | Infonet Software Solutions Inc. (Incite Software acquired from Infonet) | BC | Acquired | Info Tech |
| 1989 | Microtran Power System Analysis Corporation | BC | Active | Info Tech |
| 1989 | Vancouver Biotech Ltd. | BC | Active | Life Science |
| 1986 | Agar Technologies Inc. (Acquired by Marine BioProducts) | BC | Acquired | Life Science |
| 1986 | Freshxtend Technologies Corp. (formerly Sunblush Technologies Corporation) | Australia | Active | Physical Science |
| 1985 | Lipex Biomembranes, Inc (merged with Northern Lipids - 2000) | BC | Merged | Life Science |
| 1984 | Narod Geophysics Ltd. | BC | Active | Physical Science |
| 1983 | TIR Systems Ltd. Acquired by Phillips in 2007 | BC | Acquired | Physical Science |
| 1981 | ITA Inverse Theory & Application Ltd. (acquired by Landmark Graphics) | AB | Acquired | Info Tech |
| 1981 | QLT Inc. | BC | Active | Life Science |
| 1976 | Vortek Industries Ltd. (acquired by Mattson Technology Inc. ) | BC | Acquired | Physical Science |
